Glutathione

The body's main antioxidant tripeptide. Oral forms can raise blood levels modestly; skin-lightening evidence is small and short-term, and IV use carries real risks.

Also known as: GSH, Reduced glutathione, L-glutathione, gamma-glutamylcysteinylglycine
Area: Longevity
Status: Sold as a food supplement; not approved as a medicine in the UK or US

Articles on Glutathione

LongevityHuman RCT

Glutathione: oral, IV and topical, and what each has been shown to do

Daily oral glutathione can raise body stores modestly. Skin-lightening effects are small, short-lived and based on a few trials, while IV glutathione has little evidence and a live contamination problem.

HPR Editorial · 29 Aug 2026 · 8 min read