Kisspeptin

The hypothalamic signal that switches on GnRH release; small human trials show it can trigger egg maturation in IVF, but it is not an approved drug.

Also known as: Kisspeptin-10, Kisspeptin-54, KP-10, KP-54, Metastin
Area: Hormones
Status: Not approved as a medicine anywhere; investigational in fertility research

Articles on Kisspeptin

HormonesHuman RCT

Kisspeptin: what the IVF and brain studies in people actually found

Kisspeptin is one of the better-studied peptides in humans, mostly by one London group. It can trigger egg maturation in IVF, but it is still experimental and unapproved.

HPR Editorial · 5 Sept 2026 · 7 min read