Sermorelin

The first 29 amino acids of human GHRH; once FDA-approved for short children with GH deficiency, with only small, short studies in older adults.

Also known as: GHRH (1-29), Geref, GRF 1-29 NH2
Area: Hormones
Status: Former FDA-approved drug (Geref); maker stopped selling it in 2008 for business reasons

Articles on Sermorelin

HormonesHuman study

Sermorelin and gonadorelin: the older hormone-releasing peptides

Both were once FDA-approved medicines, and both are now discontinued in the US. Their real track records are narrower, and more medical, than their current reputations.

HPR Editorial · 29 Aug 2026 · 6 min read